Effects of anabolic steroids

Effects of anabolic steroids

We will try to explain to you, quite easily, the effect of anabolic steroids on the athlete’s body, the whole truth, as it really is.

This article is designed to protect people from deceitful information spreading on the Internet, on TV or elsewhere, about anabolic steroids.

Anabolic steroids are synthetic derivatives of testosterone, the male sex hormone, possessing both anabolic and androgenic action simultaneously, therefore, sometimes they are called anabolic-androgenic steroids (AAS).

The androgenic effect carries the negative side of testosterone, that is, all the side effects such as the development of secondary sexual characteristics, aggression, low voice, sexual attraction, the development of genital organs, and hairiness are associated with it. The anabolic effect of steroids is associated with an increase in muscle mass, that is, activation of muscle growth due to the synthesis of proteins in muscle cells.

The history of the discovery of anabolic steroids

effects of steroidsIn the first, anabolic steroid was obtained by the German biochemist Adolf Butenandt in 1931, he managed to extract 15 mg of androstenone from 10,000 l of urine.

A little later, Nazi Germany, the Netherlands and Switzerland, combining their efforts in the field of obtaining anabolic steroids, extracts from the extract of testicles an animal more powerful component, crystalline testosterone.

During the military operations in Germany, anabolic steroids were experimenting with prisoners, as are rumors that Hitler used steroids in the form of injections, according to his personal doctor. According to unconfirmed reports, the Nazis used steroids for aggression, and increased the endurance of soldiers. Other countries used AAS to restore the health of soldiers who were released from captivity.

Since 1940, steroids have begun to enter actively into the sporting life of the society, for example, the success of the USSR national weightlifting team made the US team doctor actively cooperate with chemists, in order to obtain an anabolic steroid that had minimal androgenic activity, while at the same time maximizing anabolic action , as a result, methandrostenolone was obtained. In 1956, the Directorate for Supervision of Medicines and Food Products (FDA) fully endorses the legal use of the new drug. First of all, methandrostenolone was released for tissue regeneration and regeneration in the post-burn period, as well as for pensioners, instead this steroid begins to be widely used in bodybuilding and other power sports, and in large, uncontrolled doses. As a result, mass infertility begins, and prostate hypertrophy in athletes. In 1976, the International Olympic Committee (IOC) prohibits the use of any anabolic steroids, and from this moment begins the era of hunting for athletes using so-called doping. As you can see, the thoughtless, unjustified, absolutely uncontrolled use of anabolic-androgenic steroids has led to disastrous consequences, and as a consequence, the contamination of any mention of potent drugs such as steroids.

STEROID Side Effects For Men: The SHOCKING Truth !

Basic Aspects of Understanding Anabolic Steroids

If you use testosterone in its natural form, it will quickly start to be excreted from the body, due to the fact that the half-life in the body is only 10 minutes. In addition, every ten minutes, exactly half of what is left will be excreted from the body, and after one hour nothing will remain, as you see the use of testosterone in its natural form is extremely ineffective. You can certainly put an injection into the muscle, which will lead to an increase in the duration of testosterone on the body, exactly nine hours, but this is not enough to feel at least some effect on the body. Therefore, before the scientists, the task was set to make testosterone, so that it could effectively act on orgasm. The solution to this problem was ingenious, chemists created derivatives of testosterone molecules, 17-alpha-alkylate and 1-methyl (to prevent destruction in the liver, thus making the use of steroids orally, as tablets), 17-beta ether (injection , is soluble in fats, thus accumulating in tissues, as a consequence, the duration of action is increased to two months). Thus, to date, absolutely all steroids differ only in the variation of the above derivatives of the testosterone molecule.

Underestimated androgenic properties, overestimated androgenic effect and low anabolic effect, or overestimated anabolic and androgenic action, this is what distinguishes the derivatives of the testosterone molecule, from the original substance of testosterone, which explains the different side effect, the spectrum of action, and of course the different effectiveness from the use of all existing anabolic steroids.

Anabolic and androgenic steroids are two different things, but they used to be considered vice versa. People wanted to create such a drug, which would have only anabolic benefit to athletes, without any side effects, androgenic. Now everyone understands that any steroid has an anabolic and androgenic effect on the body, only in different tissues. At the present time conditionally qualify all steroids for anabolic and androgenic, that is, steroids in which the androgenic action against testosterone is underestimated is called anabolic, where it is higher, is called androgenic.

A similar effect on the body, from the use of anabolic-androgenic steroids is associated with their common ancestor, testosterone. Consideration of all the biochemical processes occurring in the body with the use of steroids does not make sense for bodybuilding, so consider only those moments that the athlete needs to know for more competent use of AAS.

The mechanism of action of steroids

The mechanism of action of steroidsSteroids are taken by injection, that is, intramuscularly directly into the blood, taken orally in tablet form Steroids go through the gastrointestinal tract to the liver, where they are completely or partially destroyed, or enter the bloodstream in its original condition.

Having got into the blood of a steroid, in the form of steroid molecules, spreads throughout the bloodstream of a person. The purpose of the steroid molecule is to convey the information to the cells needed. The cells intended for this purpose have on the outer membrane, various receptors. The so-called steroid receptors in large quantities are contained in muscle cells. The steroid molecule is attached to the steroid receptor, skipping all other types of receptors, and vice versa, other non-steroid receptors are looking for a “necessary” molecule. When connected to the steroid receptor, steroid molecule is capable of transmitting the information of the muscle cell, but the problem is that in most of the body, about 98% of steroid molecules are bonded globulin that binds sex hormones, and only 1-2% of steroid molecules are free state, which can form a so-called steroid-receptor complex.

The steroid molecule, in conjunction with the steroid receptor, is sent to the nucleus of the muscle cell, where it joins the DNA nucleic acid segments. That is, an imprint is made with DNA (transcription). Thus, a ribonucleic acid is created that begins to leave the cell nucleus, entering the cytoplasm, it joins the RNA located here, where the protein (proteins) from the amino acids on the RNA information matrix is ​​synthesized, using ribosomes (translation). So, not in a tricky way, in combination with training in the gym, muscle hypertrophy, muscle cell growth occurs.

In addition, steroid molecules have an anti-catabolic effect, they block the cortisol receptors located on the membrane, minimizing the percentage of destruction of proteins in the muscle cell.

Due to steroids, the synthesis of creatine phosphate (CF) increases, and as you know, it plays a crucial role in the recovery of adenosine triphosphate (ATP), and this means accumulation of energy in the muscle cell. If needed, ATP passes to ADP (adenosine diphosphate) releasing a huge amount of energy, which explains the increase in strength, but not mass, for example, when used, oxandrolone (a large amount of CF in the muscle cell is synthesized). The increase in endurance from the use of steroids is explained by the fact that in the muscle cell there is an increased supply of carbohydrates in the form of glycogen, in addition there is still an increased accumulation of fluid, as a result, the volume of muscles increases.

The percentage of fat in the body is lost, while maintaining muscle mass and hardness of muscles is increased due to the fact that steroids reduce endogenous insulin, i.e. muscle cell is less dependent on insulin, and now it could metabolize the carbohydrates in the form of glycogen and protein form of amino acids.

Steroid pampus, as if the muscles pump blood with a pump, another positive effect of using steroids. The number of erythrocytes and blood volume increases muscle like balloons, blood flows more, and along with it and nutrients received together with the blood to the muscles becomes greater in connection with the body begins to be supplied with much better oxygen, so for example the effect of using runners sprint distances.

After the steroid-receptor complex has its purpose in the cell nucleus, the steroid molecule back into the bloodstream, and repeats the above-mentioned steroid cycle again, or converted into an unnecessary, having exhausted all its resources steroid molecule and appears in the urine.

Why steroids act differently on different people

The fact is that once in the blood, the steroid molecule does not immediately bind to the globulin, or is in a free, active state. Part of the steroid molecules, in the process of metabolism, can be used by the body, and then withdraw from it, and some can generally go into female sex hormones – estrogens (the phenomenon is called aromatization), with the help of enzymes (enzymes), part can go dihydrotestosterone (DHT ). It is noteworthy that dihydrotestosterone is chemically more strongly bound to muscle receptors, in contrast to testosterone, while it has a stronger, binding potential with sebaceous glands and hair follicles. Experts agree that dihydrotestosterone has a stronger steroid effect, besides DHT is not converted into estrogens.

Effects of anabolic steroidsIn any case, the spent anabolic steroids will be excreted from the body with urine.

For example, some steroids have more free steroid molecules in their arsenal that last longer in a free state, and as a result they have a better chance of finding the right steroid receptor, such drugs include Deco, Dianabol, Sustanon-250, Parabolan, Cypionate.

That is, it turns out that the more a person has free receptors in muscle cells, the more there will be the effect of steroids on the body, since free steroid molecules will have much more chances to unite into a steroid-receptor complex with a free receptor in the muscle cell.

At the age of 20 our receptors reach the peak of their activity, steroids are at the maximum level of digestibility, so it is more appropriate at this age to use anabolic steroids in order to increase muscle mass, strength and relief. But before crossing this line, natural training and training on anabolic steroids, it is necessary to take into account a lot of nuances, starting from strength indicators, ending with the expediency of their application.

It is not possible within the framework of this article to consider all those little things that form the basis for understanding anabolic steroids, but the necessary minimum that every self-respecting athlete must know.

This information about steroids was provided only for informational purposes, do not treat it as an instruction for the use of AAS. It is much more correct to protect you from a mistaken understanding of anabolic steroids.

Mexican Anabolic Steroids

The Real Facts About Mexican Anabolic Steroids

Before you wool the Internet in search of information on Mexican Anabolic Steroids the correct use of steroids, you need to answer yourself one question: what I do not like normal anabolic steroids facts athletic physique, why do I need huge muscles? Maybe it’s cool, it’s fashionable, it’s like a man? No, it’s not more than the imposed ideals. The people around you do not care what kind of muscle mass you have, how much the biceps is and what your working weight is, everyone has enough problems. Why limit yourself to cheap ideals? To look and feel great, it is enough to lead a healthy lifestyle, eat right and regularly visit the gym, without fanaticism.

Side effects of steroids

All anabolic drugs in one way or another are harmful to health, when it comes to dosages used in bodybuilding. There are several main side effects common to most steroids:
Increase in cholesterol in the blood. Prolonged anabolic steroids facts use of anabolic drugs worsens the lipid profile of the blood, the walls of the vessels narrow and lose their elasticity, they form cholesterol plaques, the breakdown of which leads to a stroke.
Active hair growth throughout the body. A sharp rise in testosterone levels activates hair growth throughout the body, even in the most undesirable areas. Along with this, some men, especially over 30, may have hair loss on the Mexican Anabolic Steroids head and partial baldness.
Pimples. Increased skin greasiness and acne are, although not the most terrible, but very unpleasant Mexican Anabolic Steroidsconsequence of the effect of anabolic substances on the body;
Toxic effects on the liver. Despite the fact that the liver is capable of self-healing, prolonged use of oral steroids can seriously disrupt its work and lead to serious consequences.
Suppression of the natural function of testosterone production. During the use of steroids in the body there is a sharp hormonal surge, in such conditions, the natural  anabolic steroids facts production of testosterone, follicle-stimulating and luteinizing hormone ceases, and it takes a long time to completely restore it.
Temporary increase of libido. During the course, sex drive greatly increases, sometimes it greatly distracts from work and even from training, but many men evaluate it positively. This phenomenon is temporary, after completion of the course, there may be problems with potency.
Heartburn. Occurs when using oral anabolics. From a temporary phenomenon, this can develop into more serious problems, for example, esophageal cancer.
Abscess. Can result from improper injection.
Premature closure of growth zones in adolescents. Under the influence of steroids, the development of the skeleton may stop prematurely, which leads to various diseases of the musculoskeletal system and internal organs.
Increased risk of cancer. Steroids do not exert a direct influence on the formation of malignant neoplasms, but they accelerate the risk of developing already existing ones. People with a predisposition to oncological diseases are at Mexican Anabolic Steroids greatest risk.
Almost anabolic steroids facts all of these actions are temporary and reversible, but is it worth testing your body for strength? Is it not better to lead a normal life, train for pleasure, not depend on tablets and not bother with muscle mass? Only you can answer these questions, because this is your health, your life, and how it will be lived depends on you.

EFFECTS OF ANABOLIC STEROIDS

Steroids actually increase size and strength. In fact, they do it very significantly. In addition to increasing strength and muscle mass, anabolic steroids provide more energy and aggressiveness, things that contribute to good training (but not in interpersonal relationships).

Psychological Effects of Anabolic

Based on the fact that steroids give you very good effects, it is not surprising that they cause psychological dependence. Imagine that you took steroids for 8 weeks, fed well and trained. During this effects of steroidstime, you have become much stronger and more. Gradually, you negate the use of steroids. In a week, after stopping their use, you will notice that you do not get a good pumping, your strength and muscle mass decreases, regardless of your efforts. Add to this the fact that during the first few weeks, after stopping the use of anabolic steroids, you will feel depressed by the low level of testosterone, and it becomes clear to you why some people do not get rid of steroids at all.

Depressive Effects of Steroids

In the period of training without anabolic steroids, when the testosterone level is low, the risk of depression at this time will be great. If you are not aware of what you are doing (using steroids with the greatest side effects, abuse dosage), you will not only provide yourself with side effects and depression during taking steroids, but also after stopping their use. Again, the degree of side effects is directly proportional to the dose and type of steroids, and also depends on the genetic predisposition of the subject. Therefore it is impossible for me or anyone else to accurately predict what side effects you may experience during the period of use. However, one thing is for certain. If you abuse the drug using it at high dosages and for a long time,

The Risks of Using Anabolic

  • Liver enlargement
  • Decrease in natural production of testosterone
  • Increased cholesterol and blood pressure
  • Changed Thyroid Function
  • Headache
  • Nasal bleeding
  • Convulsions
  • Gynecomastia
  • Insensitivity to insulin
  • Androgenic side effects, such as thinning hair, enlarged prostate, oily skin, fluid retention, increased body hair, aggressiveness
  • Growth retardation in adolescents
buying steroids in mexico

Buying Steroids in Mexico City

Bodybuilding appeared with  mexico pharmacy steroid  the advent of steroids. It’s not surprising that anyone buying steroids in mexico who trains with iron sooner or later thinks about whether to try dope or not.

There are several reasons why non-professional athletes decide to use steroids.

  1. Community impact. Athletes using steroids (“chemists”) almost always try to demonstrate their superiority over their weak comrades. The very idea of ​​a natural training is laughed at and criticized. At the same time, chemists talk about the wonderful prospects of using steroids, hiding all the mexico pharmacy steroid negative aspects. Propaganda of the application of pharma is widely spread and in the forums. Beginners are interested, and chemists buying steroids in mexico are happy to satisfy their interest Anabole Steroiden Kopen Nederland, idealizing buying steroids in mexicosteroids. Yes, it’s a fact – most of the steroids do not know how to objectively assess the pros and cons of using “pharma”. They convinced themselves of the relative safety of steroids and believe that the pros significantly outweigh the disadvantages.
  2. The desire to achieve the goal. When you work in the gym for years lichaamsportschool.com, and when you wear a sweater you are no different from “non-sportsmen”, you get disappointed and dissatisfied with yourself. After all, the goal is to get pumped up, but nothing comes out … After a close dialogue with mexico pharmacy steroid the experienced, you are exposed to the truth that without steroids training in the gym is just a physical exercise to maintain the form. After that, it remains either to adjust your goal and train for health without buying steroids in mexico any ambitions about massive muscles, or try to become Arnold with tablets.
  3.  Complexes. Many guys and men scheda palestra massa go to the gym not because they like a healthy lifestyle and physical activity, but to urgently solve their life problems through pumping muscles. They do not have much time to achieve results, the muscles were needed yesterday! In this situation, chemists will be happy to prompt you how to quickly inflate.
  4. Genetic limit. After several years Steroïden Kopen Online of training, any natural bodybuilder reaches the limit, after which it is unrealistic to gain neither strength nor weight. This is due to the fact that the body’s ability to recover after the fiznagruzok still limited and after 21-25 years with each year mexico pharmacy steroid are reduced. And, it would seem, can it be time to stop and be satisfied with the result achieved? However, it is psychologically difficult to get used to the idea that your progress in your favorite business buying steroids in mexico has stopped and is no longer possible. And here to help come steroids!

Effects of steroids

Let’s see what an amateur athlete can weigh, who weighed all the pros and cons and decided to start taking androgenic anabolic steroids. Such a person should clearly realize that if he wants to grow stably effects of steroidsenough and keep the achieved results, he will have to take steroids about 35-40 weeks per year. Believe that the recommended by the same Fred Hetfield two six-week cycles in a year on the basis of the results of the year will give almost zero result. Please understand me correctly, I do not agitate for the constant use of steroids, I just inform you how things are in practice. Do you want to check wendler 531 on your experience? Good luck. I repeat that with a rather questionable share of common sense, the intake of anabolic steroids can be justified to some extent by those athletes, who have come close to realizing their steroidless genetic potential. This means that the specific gravity of the muscle tissue should be at least 50% of the body weight. That is, at least half the weight of your body should be muscular. When using adequate dosages that for a person of average sensitivity to steroid therapy are from 0.5 to 1 milligram of the drug administered per kilogram of body weight per day (smaller doses work only in genetically gifted people, and large ones are unreasonably toxic), one can expect the following effects:

  1. increased physical performance;
  2. accelerating the growth rate of muscle mass and strength;
  3. improvement of glycogen compensation;
  4. increased power endurance;
  5. increased blood volume, improved hydration of muscle tissue;
  6. improving appetite, improving vitality, improving mood, a slight increase in aggressiveness, allowing intensive training;
  7. improving the quality of training, increasing motivation for training;
  8. provided adequate nutrition reduction of the subcutaneous fat layer while maintaining muscle mass or even some increase in it.

It is advisable to observe the following principles:

  1. The duration of taking steroids should be quite long – from 9 to 12 weeks
  2. The intake of oral (tableted) drugs should be excluded or at least reduced to 3-4 weeks at the beginning of the cycle, except for practically non-toxic for the liver primobolana, vinstrol, oxandrolone. Especially it concerns reception of such steroids, as oxymetholone, methandienone and methyltestosterone.
  3. At achievement of the expressed anabolic effect it is expedient to reduce the used dosage twice, for example having begun with a daily dose of 1 milligram per kilogram of body weight, to reduce it to 0.5 mg per kg.
  4. When working to increase muscle mass, the protein dosage should be at least 3-3.5 grams per kilogram of body weight per day, caloric content – 40 kilocalories per kilogram of body weight per day.
  5. Approximately four weeks before the end of the drug intake, exclude highly androgenic esters of testosterone.
  6. Contrary to existing “recommendations” (most often people who have never taken steroids, but consider themselves experts in this matter), do not try to maintain, after stopping the use of steroids, the previous volume and intensity of the training. In addition, that this is impossible, such attempts will have a destructive effect not only on your muscles, but also on health.

Side effects.

What undesirable side effects can you expect while taking steroids and after it stops?
Despite the hysteria, blown up by anti-steroid propaganda, the total toxicity of androgen-anabolic steroids, even at dosages 1.5-2.5 times greater than those indicated above, has not been proved by anyone. The expressed toxic effect of steroids on the body is most often manifested with prolonged use of very high doses (3-4 grams per week or more), the abuse of oral, alkylated in the 17-alpha position, drugs such as methandienone, methyltestosterone, oxymetholone, and congenital or acquired intolerance of this group of drugs. Nevertheless, with the intake of androgenic anabolic steroids, undesirable side effects can occur. Side effects should be considered all the effects that occur when taking steroids, except for direct anabolic effects on skeletal muscles. The main ones are:

  1. Symptoms of virilization, such as acne (acne), which in some cases, can be corrected by a complex of measures, including the exclusion of simple carbohydrates from the diet, hygiene measures for prevention and treatment, the use of drugs such as roaccutane and other retinoids, as well as antistaphylococcal immunoglobulin, ultraviolet irradiation. Hirsutism manifests itself in the form of increased growth of hair on the body and face, both in men and women. At times, the pathological boundaries reach an increase (reversible) libido (sexual drive) in the representatives of both sexes. In women, coarsening of the voice and irreversible hypertrophy of the clitoris can occur. The use of anabolic steroids by young people who have not reached full biological maturity leads to accelerated sexual maturation and early closure of the growth zones of tubular bones.
  2. Feminization in the form of increased fat loss and development of gynecomastia in men develops in the presence of functional liver failure and long-term use of high dosages of various testosterone esters and other drugs that are easily exposed to the process of aromatization. Therapeutic measures to combat this side effect, especially against the backdrop of the continued use of steroids, consisting in carrying out antiestrogen therapy or taking anti-aromatase drugs, are sometimes fraught with serious complications.
  3. steroidsWhen using high or even average dosages of anabolic steroids in predisposed individuals, as well as with increased sodium intake, edema and hypertension may occur. If these phenomena are not corrected by a decrease in sodium intake and intake of diuretic herbal doses, the dosage of taking steroids should be reduced or even stopped taking medications.
  4. All 17-alpha-alkylated steroids, which have already been mentioned repeatedly, are potentially hepatotoxic, only in the dosages tolerated by each individual. All other steroids, although they do not have toxicity in the reasonable dosages for the liver, but their anabolic effect on the liver leads to a thickening of the hepatic cell wall. Reinforced by the advice of not very skilled “experts”, the use of membrane protective preparations such as Essential, Karsil and Legalon, this effect leads to a significant thickening of the membrane of the hepatic cell, which complicates the secretion of bile to the bile capillaries, its normal consistency is disturbed, resulting in the development of intrahepatic cholestasis . Clinically, this is manifested by the severity in the right hypochondrium, the increase in the liver, and with considerable severity – loss of appetite, weakness, bitterness in the mouth, nausea and jaundice. After the withdrawal of drugs, these phenomena usually occur within two to three weeks. The only auxiliary hepatotropic therapy for the intake of androgenic anabolic steroids can be the use of decoctions and infusions of dog rose, immortelle, corn stigmas, in addition – the use of one or two bottles of degassed alkaline mineral water.
  5. Suppression of endogenous secretion of gonadotropins and androgens, as well as suppression of spermatogenesis, occurs after 3-5 weeks of taking androgens at a dosage equivalent to 250 mg of testosterone per week. After the withdrawal of drugs, all the mechanisms of hormonal regulation are restored naturally after 8-15 weeks. The now popular use of the chorionic gonadotropin interferes with the processes of hormonal regulation at a higher level and disrupts the natural process of restoring the normal hormonal background. The use of this drug is highly undesirable, and with a great deal of doubt can be justified by those athletes who want to minimize muscle loss during a short 3-5 week break between steroid prima cycles.
  6. Despite the opinion spread by the media, androgen-anabolic steroids do not have a carcinogenic, cancer-provoking effect. Nevertheless, androgens stimulate the growth of prostate cancer and mammary glands already present in men.
  7. With prolonged use of high doses of testosterone preparations, especially in predisposed individuals, there may be an unmotivated increase in aggression and temper tantrums.
  8. Long-term use of high doses of steroids, especially oxymetholone, leads to a pronounced suppression of immunity and a weakening of the strength of connective tissue structures – the ligamentous tendon apparatus and the internal “skeleton” of muscle tissue. Occurring in parallel with this increase in the power capacity of the muscular apparatus, can lead to injuries.
  9. Prolonged long-term use of high doses of androgens leads to irreversible hair loss on the head, especially in predisposed individuals, regardless of gender and age.

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